| Singles | — | sitcom | 3 | 22 |
| Sinister Street | — | — | — | — |
| Sir Bernard's Stately Homes | BBC Two | comedy television series | — | 6 |
| Sir Francis Drake | ITV | drama television series | 1 | 26 |
| Sir Gadabout: The Worst Knight in the Land | CITV | children's television series | 2 | 20 |
| Sir Yellow | — | sitcom | 1 | 6 |
| Sirens | Channel 4 | LGBT-related television series | 1 | 6 |
| Sirens | — | — | — | 2 |
| Sister Boniface Mysteries | BritBox | comedy drama, crime television series, mystery television series | 4 | 38 |
| Sitting on a Fortune | ITV | game show | 2 | 13 |
| Sitting Pretty | — | sitcom | — | — |
| Six Days of Justice | — | drama television series, anthology series | — | 24 |
| Six Four | ITVX | crime film, thriller | 1 | 4 |
| Six Nations: Full Contact | — | — | 1 | 8 |
| Six Shades of Black | ITV Granada | drama fiction | — | 6 |
| Sixpenny Corner | — | soap opera | — | — |
| Sixty Minutes | — | — | — | — |
| Skate Nation | — | reality television | — | — |
| Skatoony | Cartoon Network | game show, comedy television series, children's television series, live action/animated television series | 3 | 39 |
| Skin | — | — | — | — |
| Skins | E4 | drama television series, teen drama television, coming-of-age television program | 7 | 61 |
| Skint | Channel 4 | documentary television program | 3 | 11 |
| Skint | — | — | — | — |
| Skorpion | — | thriller television series | — | 6 |
| Sky | ITV | science fiction television series | 1 | 7 |
| Sky Cops | BBC One | documentary film | 2 | 17 |
| Sky News at Ten | Sky News | — | — | — |
| Sky News Sunrise | Sky News | — | — | — |
| Sky World News | — | — | — | — |
| Slap Bang with Ant & Dec | ITV | — | 1 | 6 |
| Slave Market | MBC Action, MBC 4, MBC Persia, MBC Max, MBC Shahid | drama film, historical film | 2 | 19 |
| Sleeping Dogs | — | comedy television series | — | — |
| Slinger's Day | — | sitcom | 2 | 12 |
| Slow Horses | Apple TV | espionage television series | 6 | 34 |
| Smack the Pony | Channel 4 | sitcom, sketch show | 3 | 23 |
| Small Island | BBC One | drama film | — | 2 |
| Small Potatoes | Channel 4 | sitcom | 2 | 13 |
| Small Talk | BBC One | — | 4 | 52 |
| Small Teen, Bigger World | — | documentary film | — | — |
| Small Town, Big Story | — | drama television series | 1 | 6 |
| SMart | BBC One | — | 16 | 199 |
| SMarteenies | CBeebies | — | — | 50 |
| Smile | BBC Two | — | — | — |
| Smilla's Sense of Snow | — | thriller television series, crime television series, science fiction television series, mystery television series | 1 | 6 |
| Smith and Goody | ITV | — | 1 | 7 |
| Smoggie Queens | BBC Three | British sitcom | — | — |
| Smothered | — | — | — | — |
| Smuggled | — | — | — | — |
| Smuggler's Bay | — | — | — | — |
| Snub TV | — | — | — | — |
| Snuff Box | BBC Three | comedy television series | 1 | 6 |
| Snug and Cozi | ITV | — | 2 | 16 |
| So Awkward | BBC Children's and Education | — | 2 | 13 |
| So Graham Norton | Channel 4 | comedy television series | 5 | 76 |
| So Haunt Me | BBC One | sitcom | 3 | 19 |
| So It Goes | — | — | — | — |
| So What Now? | BBC One | sitcom | — | 8 |
| So You Think You Can Dance | BBC One | talent show | 2 | 19 |
| So You Want to be Top? | BBC One | — | 3 | 18 |
| Soap Fever | ITV2 | — | — | 167 |