| Should I Marry a Murderer? | Netflix | — | — | — |
| Should I Worry About...? | BBC One | documentary film | 2 | 14 |
| Shoulder to Shoulder | — | docudrama | — | — |
| Show Me Show Me | CBeebies | — | — | 162 |
| Show Me the Funny | ITV1 | — | 1 | 7 |
| Show Me the Monet | — | — | — | — |
| Show Me the Money | — | game show | 2 | 113 |
| Show Me the Money | — | — | — | 109 |
| Show Me the Telly | — | game show | 1 | 20 |
| Show Me What You're Made Of | CBBC | children's television series, documentary television program | 7 | 25 |
| Showbiz Darts | — | game show | 1 | 15 |
| Showboaters | — | — | 1 | 8 |
| Showtrial | BBC One, British Broadcasting Corporation | drama television series, procedural, crime television series | 1 | 5 |
| Shrink Rap | — | talk show | 3 | 12 |
| Shrinks | — | — | — | — |
| Shut That Door! | ITV | talk show | — | — |
| Siblings | BBC Three | — | 2 | 12 |
| Sick Note | Sky Atlantic | comedy television series | 2 | 14 |
| Sick of It | Sky One | — | 2 | 12 |
| Side by Side | British Broadcasting Corporation | sitcom | 2 | 13 |
| Signed by Katie Price | — | reality television | 1 | 8 |
| Signora Volpe | — | detective fiction, crime fiction | 2 | 6 |
| Silent Evidence | BBC One | detective fiction | 1 | 6 |
| Silent Witness | BBC One | drama television series, crime television series | 27 | 248 |
| Silk | BBC One | crime television series | 3 | 18 |
| Silly Animals | — | comedy television series | 1 | 20 |
| Silly Pets | Sky Kids | children's television series, comedy television series | 1 | 20 |
| Silverpoint | CBBC | teen drama television, science fiction | 2 | 26 |
| Simon and the Witch | British Broadcasting Corporation | fantasy television program, comedy television series | 2 | 25 |
| Simon in the Land of Chalk Drawings | Thames Television | children's television series | 2 | 24 |
| Simon Schama's Power of Art | BBC Four | documentary film | — | 8 |
| Sin Cities | — | — | — | — |
| Sin on Saturday | BBC One | — | — | 3 |
| Sinbad | Sky One | drama television series, fantasy television series | 1 | 12 |
| Sindbad & the 7 Galaxies | — | — | — | — |
| Sing If You Can | ITV1 | game show | 1 | 6 |
| Sing: Ultimate A Cappella | — | — | — | — |
| Single Father | BBC One | drama television series | 1 | 4 |
| Singles | — | sitcom | 3 | 22 |
| Sinister Street | — | — | — | — |
| Sir Bernard's Stately Homes | BBC Two | comedy television series | — | 6 |
| Sir Francis Drake | ITV | drama television series | 1 | 26 |
| Sir Gadabout: The Worst Knight in the Land | CITV | children's television series | 2 | 20 |
| Sir Yellow | — | sitcom | 1 | 6 |
| Sirens | Channel 4 | LGBT-related television series | 1 | 6 |
| Sirens | — | — | — | 2 |
| Sister Boniface Mysteries | BritBox | comedy drama, crime television series, mystery television series | 4 | 38 |
| Sitting on a Fortune | ITV | game show | 2 | 13 |
| Sitting Pretty | — | sitcom | — | — |
| Six Days of Justice | — | drama television series, anthology series | — | 24 |
| Six Degrees (Northern Ireland) | — | — | — | — |
| Six English Towns | — | — | — | — |
| Six Four | ITVX | crime film, thriller | 1 | 4 |
| Six Nations: Full Contact | — | — | 1 | 8 |
| Six Shades of Black | ITV Granada | drama fiction | — | 6 |
| Sixpenny Corner | — | soap opera | — | — |
| Sixty Minutes | — | — | — | — |
| Skate Nation | — | reality television | — | — |
| Skatoony | Cartoon Network | game show, comedy television series, children's television series, live action/animated television series | 3 | 39 |
| Skin | — | — | — | — |